IMP-IT Subgroup analysis on revascularization extent (R-IMP IT) now published in JACC: Cardiovasuclar Interventions
JACC: Cardiovasuclar Interventions: Volume 14, Issue 6, 22 March 2021, Pages 717-719
Following the presentation from Francesco Burzotta, MD at TCT Connect 2020 (https://www.heartrecovery.com/education/education-library/clinical-relevance-of-revascularization-extent-in-protected-pci-insight-from-italian-studies) the R-IMP IT data is now published in JACC: Cardiovascular Interventions.
The aim of the study was to assess the association between the extent of coronary revascularization and survival in high risk and cardiogenic shock patients at 1-year follow up.
- More extensive revascularization achieved during Impella Protected PCI (revascularization index (RI) ≥0.67) is associated with significant reduction in the primary endpoint (all cause death, nonfatal MI, and nonfatal stroke at 1-year follow-up) for the entire study population (high-risk PCI and cardiogenic shock patients)
- Significant reduction in the secondary endpoint of all cause death in the more extensive revascularization group for the entire study population
- Better clinical outcomes in both cardiogenic shock and high-risk PCI subgroups with more complete revascularization
- Operators performing Impella-protected PCI may aim to improve late clinical outcomes by achieving more extensive revascularization
- Because better outcomes were associated with an RI ≥0.67, operators can use their clinical judgment in determining which lesions to treat since not all lesions need to be treated to achieve the clinical advantages
More available resources:
- Clinical Relevance of Revascularization Extent in Protected PCI: Insight From Italian Studies https://pubmed.ncbi.nlm.nih.gov/31422925/
- Videointerview with Dr. Cristina Aurigemma (Policlinico Gemelli, Rom) https://www.abiomed-news.de/beitrag/r-imp-it-study